Some of the major symptoms of Sickle cell are fatige, anemia, pain crises,Dactylitis(swelling of the hands or feet), arhritis, bacterial infections, splenic sequestration(sudden pooling of blood) and liver congestion, lung and heart injury, leg ulcers, aseptic necrosis and bones infarcts(death of portions of bone), eye damage, and other features.
Sickle cell is inherited like blood type or hair color. It is caused by a single letter change in the DNA. The Sickel Cell anemia is inherited as an autosomal recessive condition. The Sickel Cell trait is inherited as a autosomal dominant trait. Its passed on from parent to child. For Sickle Cell anemia to occur, the gene must be passed from both parents, so the child has two sickle cell genes. The inheritance of just one gene is called the Sickle Cell trait or the "carrier" state. Sicke cell trait does not cause someone to develope Sickle cell anemia.
The disorder is present from conception. It is not a feature that can be seen. The one way to find out if you have Sickle Cell isby a simple blood test.
Sickle cell CAN be detected before birth. They use an amniocentesis or Chorionic Vilas Sampling(CVS), where they take fluid/cells from the amniotic sac by means of a needle.
People or parents can be tested for sickle cell. Its a simple blood test called hemoglobin eletrophoresis.
The environment does not effect nor does it cause sickle cell.
Here is a foundation that helps those who have Sickle cell or knows some one who does:
Answer the following questions:
What is sickle cell?
What is the abnormal hemoglobin called?
Who gets Sicke Cell?
What are the two different types?
How can it be tested?
Go to these websites for more information:


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